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Pyson
These supplements mainly work through five basic mechanisms, namely, stimulating thermogenesis, reducing fat production, increasing lipolysis, suppressing appetite, and reducing lipid absorption. Among these nutritional supplements, the use of Plant Extracts is becoming more and more common. Garcinia cambogia extract is a typical example, and it is one of the popular weight loss materials in the United States and Japan.
The weight loss properties of Garcinia cambogia are mainly attributed to hydroxycitric acid (HCA). HCA exists in the outer skin or exocarp of Garcinia cambogia, accounting for 20-30% of the dry weight. Studies have reported that 500 mg HCA is fed to obese rats twice a day, and the results show that taking HCA can promote weight loss and fat mass, visceral fat, total cholesterol and blood glucose curve reduction in rats. The weight loss mechanism of HCA present in Garcinia cambogia studied by the researchers is mainly as follows:
(1) HCA is a competitive inhibitor of adenosine triphosphate-citrate lyase (ATP citrate lyase), which catalyzes the decomposition of citric acid into oxalacetate and Acetyl coenzyme A (Acetyl CoA) outside the mitochondria, thereby limiting In view of the availability of acetyl-CoA, acetyl-CoA plays a key role in the synthesis of fatty acids in a carbohydrate-rich diet. Therefore, HCA can inhibit the synthesis of body fat.
(2) In addition, the increase in the amount of citric acid that has not been converted into acetyl-CoA will accelerate the glycogen production of glucose. Therefore, intake of HCA can also stabilize blood glucose levels, thereby suppressing hunger and reducing intake.
What other ingredients are claimed to have weight loss
Capsaicin/Caffeine
Garcinia Cambogia/Apple Cider Vinegar
Chia seeds/konjac gum
Mulberry Leaf Extract
White Kidney Bean Extract
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